2006 Mercedes-Benz E320 problems & reliability
41 owner complaints filed with NHTSA for the 2006 Mercedes-Benz E320, alongside 4 safety recall campaigns. Last verified Aug 7, 2026. Complaints are unverified reports submitted by owners to the federal Office of Defects Investigation.
Each complaint is counted once (by NHTSA case number), even when it names several vehicles.
2 complaints report injuries (2 injured).
Most reported problems
| Component | Complaints | Share |
|---|---|---|
| Service Brakes → | 15 | 37% |
| Air Bags | 6 | 15% |
| Exterior Lighting | 4 | 10% |
| Fuel/propulsion System | 4 | 10% |
| Fuel System, Gasoline | 3 | 7% |
| Electrical System | 2 | 5% |
| Fuel System, Diesel | 2 | 5% |
| Seat Belts | 2 | 5% |
| Service Brakes, Hydraulic | 2 | 5% |
| Suspension | 2 | 5% |
Component groups as classified by NHTSA. A complaint can name more than one component, so shares may sum to more than 100%.
Common symptoms owners describe
Keyword analysis of complaint narratives; one complaint can describe several symptoms.
Mileage when problems occurred
Half of the failures with a reported odometer reading occurred by 91,468 miles (middle 50% between 60,000 and 136,042 miles), based on 33 complaints that included mileage.
Complaints by incident year
What owners report
“Vehicle had a blow out on highway. Pull onto right shoulder doing about 60mph. Pressed the brakes and would not stop. Kept pressing brake and pumping the brakes and would not stop. was going around 50mph on the shoulder. After 15 seconds of pressing the brakes, car decided to brake. Checked brake lines, brake fluid…”
Service Brakes · filed May 21, 2021
“Tl* the contact owns a 2006 mercedes-benz e320. The contact received notification of nhtsa campaign number: 19v918000 (visibility) however, the part to do the recall repair was unavailable. The contact stated that the manufacturer exceeded a reasonable amount of time for the recall repair. The dealer was not…”
Visibility · filed Jul 1, 2020
“While driving, with short beeps , the sbc in my w211 gives a short warning and fails completely. It is very risky to drive after that. With such an expensive car the reliability has been compromised. If there is a recall it would help many owners.”
Electronic Stability Control (esc) · filed Feb 26, 2020
Verbatim excerpts from complaints filed with NHTSA. Reports are not independently verified.
Federal defect investigations
- Driver Air Bag Circuit High Resistance
Preliminary Evaluation PE10017 · opened May 14, 2010 · closed Nov 24, 2010
Technical service bulletins
103 manufacturer communications (TSBs, service campaigns, warranty extensions) are on file with NHTSA for the 2006 Mercedes-Benz E320. The 10 most recent:
Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing direction of travel. Note: Sound file in attachment Cause…
LI35.30-P-058566 · Service Bulletin/Repair Instructions · issued Jul 14, 2026
Complaint There are several types of complaint about noises or poor windshield wiper wiping performance: A: Wiper blades squeaking, chattering, shuddering B: The windshield is not wiped completely (streaking) C: During…
LI82.30-P-059239 · Service Bulletin/Repair Instructions · issued May 19, 2026
Complaint Headlamp, front fog lamp leaky or fogged. Cause Fogging of the headlamps is a natural phenomenon, which can occur under certain climatic conditions. It does not lead to any technical impairment of the…
LI82.10-P-078301 · Service Bulletin/Repair Instructions · issued Apr 16, 2026
Complaint Headlamp, front fog lamp leaky or fogged Cause Fogging of the headlamps is a natural phenomenon, which can occur under certain climatic conditions. It does not lead to any technical impairment of the headlamp…
LI82.10-P-078301 · Service Bulletin/Repair Instructions · issued Mar 9, 2026
Complaint Headlamps leaking or fogged Cause The fogging of the headlamp is a natural phenomenon which can occur under certain climatic conditions. In contrast to a leaky headlamp, physical fogging does not result in a…
LI82.10-P-078307 · Service Bulletin/Repair Instructions · issued Feb 25, 2026
Complaint Headlamp, front fog lamp leaky or fogged Cause Fogging of the headlamps is a natural phenomenon, which can occur under certain climatic conditions. It does not lead to any technical impairment of the headlamp…
LI82.10-P-078301 · Service Bulletin/Repair Instructions · issued Feb 24, 2026
Complaint Headlamps leaking or fogged Cause The fogging of the headlamp is a natural phenomenon which can occur under certain climatic conditions. In contrast to a leaky headlamp, physical fogging does not result in a…
LI82.10-P-078896 · Service Bulletin/Repair Instructions · issued Feb 24, 2026
Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The clunk is heard once when changing from forward to reverse (and vice versa). Note: Sound file in…
LI33.30-P-056665 · Service Bulletin/Repair Instructions · issued Nov 15, 2025
Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The clunk is heard once when changing from forward to reverse (and vice versa). Note: Sound file in…
LI33.30-P-056665 · Service Bulletin/Repair Instructions · issued May 21, 2025
Complaint Headlamps leaking or fogged Cause The fogging of the headlamp is a natural phenomenon which can occur under certain climatic conditions. In contrast to a leaky headlamp, physical fogging does not result in a…
LI82.10-P-078896 · Service Bulletin/Repair Instructions · issued Apr 28, 2025
TSBs are repair guidance manufacturers send to dealers — they are not recalls and repairs are not automatically free. Full documents are available on NHTSA’s site.
Safety recalls
The 2006 Mercedes-Benz E320 has 4 NHTSA recall campaigns — recall repairs are free at franchised dealers regardless of the vehicle’s age.
Check whether your specific vehicle is affected
Recall campaigns often cover only certain VIN ranges. Enter your VIN on the official NHTSA site to confirm whether your vehicle is included and whether the repair is still open.
Check VIN on NHTSA →Buying a used 2006 Mercedes-Benz E320?
- · Decode the seller’s VIN with our free VIN decoder to confirm the exact year, engine and trim.
- · Check for unrepaired recalls by VIN on NHTSA’s official lookup — recall repairs are free.
- · Owners most often reported problems around 91,468 miles — budget accordingly if the car is approaching that mileage.