2022 Mercedes-Benz S 500 problems & reliability
20 owner complaints filed with NHTSA for the 2022 Mercedes-Benz S 500, alongside 8 safety recall campaigns. Last verified Aug 8, 2026. Complaints are unverified reports submitted by owners to the federal Office of Defects Investigation.
Each complaint is counted once (by NHTSA case number), even when it names several vehicles.
1 complaint report injuries (2 injured).
Most reported problems
| Component | Complaints | Share |
|---|---|---|
| Forward Collision Avoidance | 8 | 40% |
| Electrical System | 6 | 30% |
| Fuel System, Gasoline | 3 | 15% |
| Structure | 3 | 15% |
| Vehicle Speed Control | 3 | 15% |
| Service Brakes | 2 | 10% |
| Tires | 2 | 10% |
| Back Over Prevention | 1 | 5% |
| Communication | 1 | 5% |
| Engine | 1 | 5% |
Component groups as classified by NHTSA. A complaint can name more than one component, so shares may sum to more than 100%.
All 15 reported components →Complaints by incident year
What owners report
“The factory upgrade 21 inch spoke wheels with Pirelli P-Zero low profile tires are averaging a blow out every 800 miles. 5 flats and 2 sidewall blisters in the last 10,000 miles. Pirelli P-Zero 255/35/R21 Front and 285/30/R21 Rear are all four available for inspection if you tell me to save them before I replace them…”
Wheels · filed Jul 1, 2026
“The following pictures will again show the issues that I'm having while driving my 2022 S Class Mercedes, while using the cruise control on the Belt Parkway. It shows me stuck in traffic and, although I can only go 11 miles an hour while I’m stuck in traffic, the cruise control wants to push it to 80 mph, which is…”
Vehicle Speed Control · filed Mar 31, 2025
“Here we go again, while driving on a side road with a 20 mph school speed limit, the cruise control wants to SPEED UP to 60 mph!! WHAT IS IT GOING TO TAKE TO REMEDY THIS BEFORE I’M INVOLVED IN A SERIOUS ACCIDENT!!”
Vehicle Speed Control · filed Mar 27, 2025
Verbatim excerpts from complaints filed with NHTSA. Reports are not independently verified.
Technical service bulletins
295 manufacturer communications (TSBs, service campaigns, warranty extensions) are on file with NHTSA for the 2022 Mercedes-Benz S 500. The 10 most recent:
This NCU replaces the prior NCU issued on May 15, 2025, and contains additional MY 2023 and MY 2024 vehicles which are highlighted below. In our continuing efforts to ensure the proper performance of Mercedes-Benz…
EW - DMTL · Warranty Program/Extension · issued Jul 31, 2026
Complaint Crackling and cracking noise from the outer wheel on the front axle when cornering Cause The noise is generated by a micromovement on the contact surface between the rim and the brake disk (wheel bolt group)…
LI40.10-P-059248 · Service Bulletin/Repair Instructions · issued Jul 21, 2026
Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing direction of travel. Note: Sound file in attachment Cause…
LI35.30-P-058566 · Service Bulletin/Repair Instructions · issued Jul 14, 2026
Complaint Traffic sign symbol for "Traffic Sign Assist" is blinking in instrument cluster without obvious cause usually with one of the following scenarios: • Flashing without a speed limit ("- -"). • Flashing when…
LI54.71-P-079104 · Service Bulletin/Repair Instructions · issued Jul 9, 2026
Complaint Creaking noise, in irregular sequence when driving slowly in combination with slight steering movements and/or Creaking/crackling noises from the area of the wheel bearing on the front axle when cornering/…
LI33.20-P-078406 · Service Bulletin/Repair Instructions · issued Jul 8, 2026
Complaint Creaking noise, in irregular sequence when driving slowly in combination with slight steering movements and/or Creaking/crackling noises from the area of the wheel bearing on the front axle when cornering/…
LI33.20-P-078406 · Service Bulletin/Repair Instructions · issued Jul 7, 2026
Dear Mercedes-Benz USA Dealers, The part numbers listed in the chart below should no longer be installed, and any existing stock must be returned to your facing PDC. The deadline for all dealer returns is no later than…
PSL-NCU Return Parts 7/3 · Other · issued Jul 3, 2026
Complaint 1. "Perform vehicle handover" in the workshop menu to start the maintenance computer for service A/B cannot be carried out. 2. Service confirmation is not possible because "Perform vehicle handover" is…
LI00.20-P-077615 · Service Bulletin/Repair Instructions · issued Jul 1, 2026
Complaint General information on the operation of the PRE-SAFE® Impulse system: The PRE-SAFE® Side Impulse system is a preventive, i.e. pre-collision occupant protection system. The task of the system is to provide…
LI54.30-P-080649 · Service Bulletin/Repair Instructions · issued Jul 1, 2026
For awareness, after SW update of control unit, IC223, on models 223 and 297, seat belt lamp and chime remains on. Thank you for your patience while we find a solution.
ANN - S/223_EQS/297 · Other · issued Jun 25, 2026
TSBs are repair guidance manufacturers send to dealers — they are not recalls and repairs are not automatically free. Full documents are available on NHTSA’s site.
Safety recalls
The 2022 Mercedes-Benz S 500 has 8 NHTSA recall campaigns — recall repairs are free at franchised dealers regardless of the vehicle’s age.
Check whether your specific vehicle is affected
Recall campaigns often cover only certain VIN ranges. Enter your VIN on the official NHTSA site to confirm whether your vehicle is included and whether the repair is still open.
Check VIN on NHTSA →Buying a used 2022 Mercedes-Benz S 500?
- · Decode the seller’s VIN with our free VIN decoder to confirm the exact year, engine and trim.
- · Check for unrepaired recalls by VIN on NHTSA’s official lookup — recall repairs are free.