2022 Mercedes-Benz S 500 4MATIC problems & reliability
21 owner complaints filed with NHTSA for the 2022 Mercedes-Benz S 500 4MATIC, alongside 8 safety recall campaigns. Last verified Oct 8, 2026. Complaints are unverified reports submitted by owners to the federal Office of Defects Investigation.
Each complaint is counted once (by NHTSA case number), even when it names several components.
1 complaint report injuries (2 injured).
Most reported problems
| Component | Complaints | Share |
|---|---|---|
| Forward Collision Avoidance | 8 | 38% |
| Electrical System | 6 | 29% |
| Fuel System, Gasoline | 3 | 14% |
| Structure | 3 | 14% |
| Vehicle Speed Control | 3 | 14% |
| Service Brakes | 2 | 10% |
| Tires | 2 | 10% |
| Air Bags | 1 | 5% |
| Back Over Prevention | 1 | 5% |
| Communication | 1 | 5% |
Component groups as classified by NHTSA. A complaint can name more than one component, so shares may sum to more than 100%.
All 16 reported components →Complaints by incident year
What owners report
“Left front windows airbag malfunctioned and had to be totally replaced. Airbag shorted internally. Fault code B002111.”
Air Bags · filed Sep 22, 2026
“The factory upgrade 21 inch spoke wheels with Pirelli P-Zero low profile tires are averaging a blow out every 800 miles. 5 flats and 2 sidewall blisters in the last 10,000 miles. Pirelli P-Zero 255/35/R21 Front and 285/30/R21 Rear are all four available for inspection if you tell me to save them before I replace them…”
Wheels · filed Jul 1, 2026
“The following pictures will again show the issues that I'm having while driving my 2022 S Class Mercedes, while using the cruise control on the Belt Parkway. It shows me stuck in traffic and, although I can only go 11 miles an hour while I’m stuck in traffic, the cruise control wants to push it to 80 mph, which is…”
Forward Collision Avoidance · filed Mar 31, 2025
Verbatim excerpts from complaints filed with NHTSA. Reports are not independently verified.
Technical service bulletins
319 manufacturer communications (TSBs, service campaigns, warranty extensions) are on file with NHTSA for the 2022 Mercedes-Benz S 500 4MATIC. The 10 most recent:
Complaint Slight creaking noises when steering. Cause Noises may come from one or more sleeves of the horn contact plate. Remedy Remove the horn contact plate and check the sleeves for noise; see attached video. If…
LI46.10-P-080896 · Service Bulletin/Repair Instructions · issued Sep 26, 2026
Complaint Customer complaints relating to automatic transmission 725.0 (NAG3 Classic /9G‑TRONIC automatic transmission) and 725.1 (NAG3 facelift/9G‑TRONIC automatic transmission facelift) For faster, more effective and…
LI27.00-P-073124 · Service Bulletin/Repair Instructions · issued Sep 26, 2026
Complaint Sporadic warning message in instrument cluster "Engine oil pressure, stop switch off vehicle" (or similar) is shown in red on vehicles with low mileage. Cause Directional control valve may stick. Remedy 1‑…
LI18.00-P-073137 · Service Bulletin/Repair Instructions · issued Sep 26, 2026
A software update will be performed that provides enhancements to the robustness and system stability of the communication module. The update is free of charge and runs in the background, which takes about 8 minutes to…
OTA-Comm. Mod. SW. Update · Over The Air · issued Sep 25, 2026
Complaint CEL illuminates and/or AC does not blow cold. Cause Potentially relevance to hardware and/or software Remedy Scenario 1: 1. If the AC does not blow cold air, replace compressor (if compressor's index and part…
LI83.90-P-080935 · Service Bulletin/Repair Instructions · issued Sep 25, 2026
Complaint Repeat workshop visit for vehicle vibration while braking from 60MPH. NOTE: Although the symptom is similar to a tire or wheel vibration, it is usually readily noticeable that it is distinctly different if it…
LI42.10-P-078779 · Service Bulletin/Repair Instructions · issued Sep 22, 2026
Dear Dealer Partners, The part numbers listed in the chart below should no longer be installed and any existing stock must be returned to your facing PDC. The deadline for all dealer returns is Thursday, October 8th…
PSL-NCU Return Parts 9/18 · Other · issued Sep 18, 2026
Complaint Red coolant warning in instrument cluster. Fault codes U019F00 or U019F87 current/stored in MRG1 control unit. Cause Various causes Remedy Perform guided test for fault code U019F with XENTRY diagnosis. Verify…
LI20.10-P-075374 · Service Bulletin/Repair Instructions · issued Sep 17, 2026
Complaint Issue after OTA Update IC Odometer Reading blank("_ _ _ _") IC Maintanence data unavailable Cause OTA Update E61.0 Remedy In the IC Control Unit Log, please check the following information: Verify whether DTCs…
LI54.30-P-080963 · Service Bulletin/Repair Instructions · issued Sep 17, 2026
Complaint Clanking noise from the area of the speakers in the doors. Cause Under analysis. Remedy To narrow down the cause, first of all remove the door trim. • If the noise continues to occur even with the door trim…
LI82.62-P-078631 · Service Bulletin/Repair Instructions · issued Sep 14, 2026
TSBs are repair guidance manufacturers send to dealers — they are not recalls and repairs are not automatically free. Full documents are available on NHTSA’s site.
Safety recalls
The 2022 Mercedes-Benz S 500 4MATIC has 8 NHTSA recall campaigns — recall repairs are free at franchised dealers regardless of the vehicle’s age.
Check whether your specific vehicle is affected
Recall campaigns often cover only certain VIN ranges. Enter your VIN on the official NHTSA site to confirm whether your vehicle is included and whether the repair is still open.
Check VIN on NHTSA →Buying a used 2022 Mercedes-Benz S 500 4MATIC?
- · Decode the seller’s VIN with our free VIN decoder to confirm the exact year, engine and trim.
- · Check for unrepaired recalls by VIN on NHTSA’s official lookup — recall repairs are free.